Searching therapeutic strategy of new coronavirus pneumonia from angiotensin-converting enzyme 2: the target of COVID-19 and SARS-CoV
Identifieur interne : 000185 ( Main/Exploration ); précédent : 000184; suivant : 000186Searching therapeutic strategy of new coronavirus pneumonia from angiotensin-converting enzyme 2: the target of COVID-19 and SARS-CoV
Auteurs : Shu-Ren Li ; Zi-Jian Tang [République populaire de Chine] ; Zai-Han Li ; Xuan Liu [République populaire de Chine]Source :
- European Journal of Clinical Microbiology & Infectious Diseases [ 0934-9723 ] ; 2020.
Abstract
Since December 2019, the infection of the new coronavirus (COVID-19) caused an outbreak of new coronavirus pneumonia in Wuhan, China, and caused great public concern. Both COVID-19 and SARS-CoV belong to the coronavirus family and both invade target cells through ACE2. An in-depth understanding of ACE2 and a series of physiological and physiological changes caused by the virus invading the human body may help to discover and explain the corresponding clinical phenomena and then deal with them timely. In addition, ACE2 is a potential therapeutic target. This article will summarize the role of ACE2 in multiple organ damage caused by COVID-19 and SARS-CoV, targeted blocking drugs against ACE2, and drugs that inhibit inflammation in order to provide the basis for subsequent related research, diagnosis and treatment, and drug development.
Url:
DOI: 10.1007/s10096-020-03883-y
PubMed: 32285293
PubMed Central: 7152693
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000147
- to stream Pmc, to step Curation: 000147
- to stream Pmc, to step Checkpoint: 000146
- to stream Ncbi, to step Merge: 000D75
- to stream Ncbi, to step Curation: 000D75
- to stream Ncbi, to step Checkpoint: 000D75
- to stream Main, to step Merge: 000185
- to stream Main, to step Curation: 000185
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Searching therapeutic strategy of new coronavirus pneumonia from angiotensin-converting enzyme 2: the target of COVID-19 and SARS-CoV</title><author><name sortKey="Li, Shu Ren" sort="Li, Shu Ren" uniqKey="Li S" first="Shu-Ren" last="Li">Shu-Ren Li</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.440208.a</institution-id><institution>Hebei General Hospital,</institution></institution-wrap>Shijiazhuang, 050051 Hebei China</nlm:aff><wicri:noCountry code="subfield">050051 Hebei China</wicri:noCountry></affiliation></author><author><name sortKey="Tang, Zi Jian" sort="Tang, Zi Jian" uniqKey="Tang Z" first="Zi-Jian" last="Tang">Zi-Jian Tang</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.440208.a</institution-id><institution>Hebei General Hospital,</institution></institution-wrap>Shijiazhuang, 050051 Hebei China</nlm:aff><wicri:noCountry code="subfield">050051 Hebei China</wicri:noCountry></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.256883.2</institution-id><institution-id institution-id-type="ISNI">0000 0004 1760 8442</institution-id><institution>Hebei General Hospital,</institution><institution>Graduate School of Hebei Medical University,</institution></institution-wrap>Shijiazhuang, 050000 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shijiazhuang</wicri:regionArea></affiliation></author><author><name sortKey="Li, Zai Han" sort="Li, Zai Han" uniqKey="Li Z" first="Zai-Han" last="Li">Zai-Han Li</name><affiliation><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="GRID">grid.263761.7</institution-id><institution-id institution-id-type="ISNI">0000 0001 0198 0694</institution-id><institution>Suzhou University,</institution></institution-wrap>Suzhou, 215000 Jiangsu China</nlm:aff><wicri:noCountry code="subfield">215000 Jiangsu China</wicri:noCountry></affiliation></author><author><name sortKey="Liu, Xuan" sort="Liu, Xuan" uniqKey="Liu X" first="Xuan" last="Liu">Xuan Liu</name><affiliation wicri:level="1"><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="GRID">grid.452582.c</institution-id><institution>The Fourth Hospital of Hebei Medical University,</institution></institution-wrap>Shijiazhuang, 050000 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shijiazhuang</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">32285293</idno><idno type="pmc">7152693</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152693</idno><idno type="RBID">PMC:7152693</idno><idno type="doi">10.1007/s10096-020-03883-y</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000147</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000147</idno><idno type="wicri:Area/Pmc/Curation">000147</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000147</idno><idno type="wicri:Area/Pmc/Checkpoint">000146</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000146</idno><idno type="wicri:Area/Ncbi/Merge">000D75</idno><idno type="wicri:Area/Ncbi/Curation">000D75</idno><idno type="wicri:Area/Ncbi/Checkpoint">000D75</idno><idno type="wicri:doubleKey">0934-9723:2020:Li S:searching:therapeutic:strategy</idno><idno type="wicri:Area/Main/Merge">000185</idno><idno type="wicri:Area/Main/Curation">000185</idno><idno type="wicri:Area/Main/Exploration">000185</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Searching therapeutic strategy of new coronavirus pneumonia from angiotensin-converting enzyme 2: the target of COVID-19 and SARS-CoV</title><author><name sortKey="Li, Shu Ren" sort="Li, Shu Ren" uniqKey="Li S" first="Shu-Ren" last="Li">Shu-Ren Li</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.440208.a</institution-id><institution>Hebei General Hospital,</institution></institution-wrap>Shijiazhuang, 050051 Hebei China</nlm:aff><wicri:noCountry code="subfield">050051 Hebei China</wicri:noCountry></affiliation></author><author><name sortKey="Tang, Zi Jian" sort="Tang, Zi Jian" uniqKey="Tang Z" first="Zi-Jian" last="Tang">Zi-Jian Tang</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.440208.a</institution-id><institution>Hebei General Hospital,</institution></institution-wrap>Shijiazhuang, 050051 Hebei China</nlm:aff><wicri:noCountry code="subfield">050051 Hebei China</wicri:noCountry></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.256883.2</institution-id><institution-id institution-id-type="ISNI">0000 0004 1760 8442</institution-id><institution>Hebei General Hospital,</institution><institution>Graduate School of Hebei Medical University,</institution></institution-wrap>Shijiazhuang, 050000 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shijiazhuang</wicri:regionArea></affiliation></author><author><name sortKey="Li, Zai Han" sort="Li, Zai Han" uniqKey="Li Z" first="Zai-Han" last="Li">Zai-Han Li</name><affiliation><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="GRID">grid.263761.7</institution-id><institution-id institution-id-type="ISNI">0000 0001 0198 0694</institution-id><institution>Suzhou University,</institution></institution-wrap>Suzhou, 215000 Jiangsu China</nlm:aff><wicri:noCountry code="subfield">215000 Jiangsu China</wicri:noCountry></affiliation></author><author><name sortKey="Liu, Xuan" sort="Liu, Xuan" uniqKey="Liu X" first="Xuan" last="Liu">Xuan Liu</name><affiliation wicri:level="1"><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="GRID">grid.452582.c</institution-id><institution>The Fourth Hospital of Hebei Medical University,</institution></institution-wrap>Shijiazhuang, 050000 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shijiazhuang</wicri:regionArea></affiliation></author></analytic><series><title level="j">European Journal of Clinical Microbiology & Infectious Diseases</title><idno type="ISSN">0934-9723</idno><idno type="eISSN">1435-4373</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">Since December 2019, the infection of the new coronavirus (COVID-19) caused an outbreak of new coronavirus pneumonia in Wuhan, China, and caused great public concern. Both COVID-19 and SARS-CoV belong to the coronavirus family and both invade target cells through ACE2. An in-depth understanding of ACE2 and a series of physiological and physiological changes caused by the virus invading the human body may help to discover and explain the corresponding clinical phenomena and then deal with them timely. In addition, ACE2 is a potential therapeutic target. This article will summarize the role of ACE2 in multiple organ damage caused by COVID-19 and SARS-CoV, targeted blocking drugs against ACE2, and drugs that inhibit inflammation in order to provide the basis for subsequent related research, diagnosis and treatment, and drug development.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Donoghue, M" uniqKey="Donoghue M">M Donoghue</name></author><author><name sortKey="Hsieh, F" uniqKey="Hsieh F">F Hsieh</name></author><author><name sortKey="Baronas, E" uniqKey="Baronas E">E Baronas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ocaranza, M" uniqKey="Ocaranza M">M Ocaranza</name></author><author><name sortKey="Michea, L" uniqKey="Michea L">L Michea</name></author><author><name sortKey="Chiong, M" uniqKey="Chiong M">M Chiong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Tikellis, C" uniqKey="Tikellis C">C Tikellis</name></author><author><name sortKey="Thomas, M" uniqKey="Thomas M">M Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Prabakaran, P" uniqKey="Prabakaran P">P Prabakaran</name></author><author><name sortKey="Xiao, X" uniqKey="Xiao X">X Xiao</name></author><author><name sortKey="Dimitrov, D" uniqKey="Dimitrov D">D Dimitrov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oudit, G" uniqKey="Oudit G">G Oudit</name></author><author><name sortKey="Kassiri, Z" uniqKey="Kassiri Z">Z Kassiri</name></author><author><name sortKey="Jiang, C" uniqKey="Jiang C">C Jiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferrario, C" uniqKey="Ferrario C">C Ferrario</name></author><author><name sortKey="Mullick, A" uniqKey="Mullick A">A Mullick</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Antoniak, S" uniqKey="Antoniak S">S Antoniak</name></author><author><name sortKey="Cardenas, J" uniqKey="Cardenas J">J Cardenas</name></author><author><name sortKey="Buczek, L" uniqKey="Buczek L">L Buczek</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kuba, K" uniqKey="Kuba K">K Kuba</name></author><author><name sortKey="Imai, Y" uniqKey="Imai Y">Y Imai</name></author><author><name sortKey="Rao, S" uniqKey="Rao S">S Rao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Imai, Y" uniqKey="Imai Y">Y Imai</name></author><author><name sortKey="Kuba, K" uniqKey="Kuba K">K Kuba</name></author><author><name sortKey="Rao, S" uniqKey="Rao S">S Rao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Yh" uniqKey="Zhang Y">YH Zhang</name></author><author><name sortKey="Gong, Lk" uniqKey="Gong L">LK Gong</name></author><author><name sortKey="Jin, R" uniqKey="Jin R">R Jin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jia, H" uniqKey="Jia H">H Jia</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hashimoto, T" uniqKey="Hashimoto T">T Hashimoto</name></author><author><name sortKey="Perlot, T" uniqKey="Perlot T">T Perlot</name></author><author><name sortKey="Rehman, A" uniqKey="Rehman A">A Rehman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khajah, M" uniqKey="Khajah M">M Khajah</name></author><author><name sortKey="Fateel, M" uniqKey="Fateel M">M Fateel</name></author><author><name sortKey="Ananthalakshmi, K" uniqKey="Ananthalakshmi K">K Ananthalakshmi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fraga Silva, R" uniqKey="Fraga Silva R">R Fraga-Silva</name></author><author><name sortKey="Sorg, B" uniqKey="Sorg B">B Sorg</name></author><author><name sortKey="Wankhede, M" uniqKey="Wankhede M">M Wankhede</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Han, Dp" uniqKey="Han D">DP Han</name></author><author><name sortKey="Penn Nicholson, A" uniqKey="Penn Nicholson A">A Penn-Nicholson</name></author><author><name sortKey="Cho, Mw" uniqKey="Cho M">MW Cho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huentelman, Mj" uniqKey="Huentelman M">MJ Huentelman</name></author><author><name sortKey="Zubcevic, J" uniqKey="Zubcevic J">J Zubcevic</name></author><author><name sortKey="Hernandez Prada, Ja" uniqKey="Hernandez Prada J">JA Hernandez Prada</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Henry, C" uniqKey="Henry C">C Henry</name></author><author><name sortKey="Zaizafoun, M" uniqKey="Zaizafoun M">M Zaizafoun</name></author><author><name sortKey="Stock, E" uniqKey="Stock E">E Stock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferrario, C" uniqKey="Ferrario C">C Ferrario</name></author><author><name sortKey="Jessup, J" uniqKey="Jessup J">J Jessup</name></author><author><name sortKey="Chappell, M" uniqKey="Chappell M">M Chappell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khan, A" uniqKey="Khan A">A Khan</name></author><author><name sortKey="Benthin, C" uniqKey="Benthin C">C Benthin</name></author><author><name sortKey="Zeno, B" uniqKey="Zeno B">B Zeno</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Li, S" uniqKey="Li S">S Li</name></author><author><name sortKey="Hao, X" uniqKey="Hao X">X Hao</name></author><author><name sortKey="Xiao, S" uniqKey="Xiao S">S Xiao</name></author><author><name sortKey="Xun, L" uniqKey="Xun L">L Xun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qu Ga, J" uniqKey="Qu Ga J">J Qu Ga</name></author><author><name sortKey="Liao, L" uniqKey="Liao L">L Liao</name></author><author><name sortKey="Hu, K" uniqKey="Hu K">K Hu</name></author></analytic></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><noCountry><name sortKey="Li, Shu Ren" sort="Li, Shu Ren" uniqKey="Li S" first="Shu-Ren" last="Li">Shu-Ren Li</name><name sortKey="Li, Zai Han" sort="Li, Zai Han" uniqKey="Li Z" first="Zai-Han" last="Li">Zai-Han Li</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Tang, Zi Jian" sort="Tang, Zi Jian" uniqKey="Tang Z" first="Zi-Jian" last="Tang">Zi-Jian Tang</name></noRegion><name sortKey="Liu, Xuan" sort="Liu, Xuan" uniqKey="Liu X" first="Xuan" last="Liu">Xuan Liu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/StressCovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000185 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000185 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= StressCovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7152693
|texte= Searching therapeutic strategy of new coronavirus pneumonia from angiotensin-converting enzyme 2: the target of COVID-19 and SARS-CoV
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32285293" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a StressCovidV1
| This area was generated with Dilib version V0.6.33. |  |